NYU LANGONE HEALTH / NYU SCHOOL OF MEDICINE VIA- EurekAlert.org
People with and without cancer are more likely, over time, to use a more potent form of medical marijuana with increasingly higher amounts of tetrahydrocannabinol (THC), a new study shows.
In a report publishing in the Journal of Palliative Medicine on March 26, researchers say that cancer patients were more likely to favor forms of medical marijuana with higher amounts of THC, which relieves cancer symptoms and the side effects of cancer treatment, including chronic pain, weight loss, and nausea.
By contrast, marijuana formulations higher in cannabidiol (CBD), which has been shown to reduce seizures and inflammation in other studies, were more popular among non-cancer patients, including those with epilepsy and multiple sclerosis, say the study authors.
Cancer patients were also more likely to prefer taking oil droplets containing medical marijuana under the tongue than "vaping".
"Although there is growing patient interest in medical cannabis, there is a scarcity of solid evidence about the benefits, risks, and patterns of use of marijuana products in various disease settings," says study lead investigator Arum Kim, MD, an assistant professor of medicine and rehabilitation medicine at NYU School of Medicine and director of the supportive oncology program at its Perlmutter Cancer Center. "Such information is important for delivering the best care."
Since 1996, 31 states, including New York in 2014, have legalized medical marijuana.
For the study, researchers analyzed data from 11,590 men and women in New York, of whom 1,990 (17.2 percent of the total patient cohort) were cancer patients who purchased and used cannabis products from Columbia Care LLC., a dispensary licensed in New York State, between January 2016 and December 2017.
The researchers caution that their data did not include the type of cancer the purchasers had, how much of what they bought was used, or whether marijuana was used for symptoms unrelated to the cancer. Nevertheless, the patterns of use among cancer patients were distinctly different from those of non-cancer patients.
Specifically, the study found that cancer and non-cancer patients used different dosages of cannabis formulations with dramatically different THC:CBD ratios. The two most common formulations contained THC and CBD, but one had twenty times more THC than CBD, whereas the other had the opposite ratio.
Over the two years of the study, the research team found that all types of patients increased their THC dose by approximately 0.20 milligrams per week.
"Our study provides valuable new information about how cancer patients are using marijuana," says study senior investigator Benjamin Han, MD, MPH, an assistant professor of medicine and population health at NYU School of Medicine. "In the absence of strong clinical research data for medical marijuana, identifying patterns of use offers some sense of how to guide patients who come in with questions for using medical marijuana, and what may or may not help them." Researchers say they next plan to get more detailed information about how medical marijuana affects patient response to therapy and functional status at different stages of their disease, as well as the risks and side effects of treatment. Furthermore, the profiles of other cannabinoids besides THC and CBD in medical marijuana products warrant further research, according to the study authors.
TALLAHASSEE -Without much debate and two. days before Gov. Ron DeSantis’ deadline, a bill to repeal a ban on smoking medical marijuana has finally rolled onto the governor’s desk. The Florida House affirmed the right to smoke medical pot Wednesday afternoon, approving the Senate bill to include “smoking” to the language in the medical marijuana constitutional amendment. The bill allows patients to receive up to 2.5 ounces of whole flower cannabis every 35 days as recommended by their qualified doctor.
Read more here: https://www.miamiherald.com/news/health-care/article227611364.html#storylink=cpy
BERKELEY (CBS SF) – The University of California at Berkeley has launched the Cannabis Research Center that will explore the impacts of cannabis production on the environment and society, UC officials said Tuesday.
The center will focus on three distinct areas of research as they relate to cannabis production: policy and regulation, environmental impacts, and cannabis-producing communities.
Van Butsic and Ted Grantham, who both work in UC Berkeley’s Department of Environmental Science, Policy and Management, will lead the center’s multidisciplinary team.
“This is a rapidly changing industry, and no one really knows where it is headed,” Grantham said in a statement. “We believe researchers have an important role in bringing independent scientific information to conversations around cannabis policy.”
While other research groups are exploring the health effects of cannabis use, this center will be the first in the UC system to explore other dimensions of cannabis growth, university officials said.
(Bloomberg) — The Super Bowl isn’t ready for medical marijuana.
Acreage Holdings, the multi-state cannabis company backed by John Boehner, says CBS rejected a television advertisement that calls for the legalization of medical marijuana. The network, which is airing the game on Feb. 3, nixed the proposed spot after seeing a rough outline, according to the company.
While medical marijuana is now legal in more than 30 states, the federal prohibition on cannabis has restricted research and made it difficult for some potential patients to get their hands on a drug that proponents say helps treat seizures, pain and other ailments.
The advertisement aimed to “create an advocacy campaign for constituents who are being lost in the dialogue,” Acreage President George Allen said. Super Bowl airtime would have been the best way to achieve this, he added.
“It’s hard to compete with the amount of attention something gets when it airs during the Super Bowl,” Allen said in a telephone interview. CBS didn’t immediately reply to a request for comment on Monday, which was a federal holiday.
The Super Bowl is typically the most-watched television program of the year, and it’s an opportunity for brands to get in front of millions of Americans. Companies typically debut new publicity campaigns and air their most creative commercials during the event. Some viewers eagerly anticipate the advertisements that run during stoppages in play.
In past years, some advertisers have also grabbed the spotlight for offering up commercials that weren’t likely to be approved.
Acreage, one of the most valuable U.S. weed companies with a market value of more than $2.4 billion, had hoped to raise its profile and push for increased access to medical marijuana. The proposed ad features two subjects who have benefited from medicinal cannabis: a veteran with combat injuries and a child with seizures.
Super Bowl ads are expensive, reportedly costing more than $5 million for an average 30-second spot last year. Acreage, which went public in Canada last year, was prepared to pony up, and created the ad thinking it had a legitimate chance of getting onto the air. The company said it was careful to position the spot as a “call to political action” rather than a pitch for its brand, which now has cannabis operations in roughly 15 states.
“We certainly thought there was a chance,” Allen said. “You strike when the chance of your strike has the probability of success — this isn’t a doomed mission.”
Glazed & Confuzed donuts founder and CEO Josh Schwab tops a donut frosted with CBD-infused glaze with a candied hemp leaf at his shop in the Stanley Marketplace in Aurora. TREVOR HUGHES, TREVOR HUGHES-USA TODAY NETWORK
TREVOR HUGHES | USA TODAY| January 10, 2019
DENVER – Sprinkled on donuts, mixed into milkshakes or infused into olive oil, make no mistake: Cannabis is coming to a kitchen near you.
Chefs across the country say cannabis-infused food and drinks are the top two dining trends they expect to see unfold in 2019, although we’re not talking about food that will get you “high" – these are products made with "CBD," a non-psychoactive compound extracted from cannabis plants that enthusiasts say offers health benefits while tempting the palate.
"I'm telling you, 75 percent of my clientele is doctors, nurses and lawyers," said Josh Schwab, 45, whose Denver-area Glazed & Confuzed donut shop makes a CBD-frosted donut topped with a candied hemp leaf, selling upwards of 30 each weekend day. "You get all the relaxation without the head high. It kinda just takes the edge off."
Jonathan Eppers, 35, has seen the rocketing CBD interest firsthand: Launched just a year ago from LA, his CBD-infused Vybes drinks are now available in 19 states, including New York and Florida, in flavors ranging from blueberry mint to blackberry lavender.
"I was tired of living every day anxious. I wanted to be more present and calm. That’s what CBD does for me," said Eppers, whose fledgling company sold more than 1.1 million bottles last year.
The survey of chefs was part of an annual poll conducted for the National Restaurant Association, which checked with more than 650 professional chefs. Of those, 77 percent said CBD drinks are the No. 1 trend they see for 2019, followed by CBD foods.Zero-waste kitchens were the third top trend identified by the chefs, who are all members of the American Culinary Federation, and who have previously singled out artisanal cheese, house-made condiments and savory desserts.
And heads-up: These same chefs say pretzels in desserts are on their way out.
Hudson Riehle, the restaurant association's senior research director, said it's still too early to tell if CBD is just a fad or will fade into history like molecular gastronomy or meals served in mason jars. U.S. restaurants are an $850 billion industry that employs about 15 million people, and the daily conversations chefs have with customers help inform the survey, said Riehle, 65.
Because CBD products are often derived from hemp, which is usually imported but legal nationally, you can expect to see CBD on menus across the United States, although specific regulations still vary.
And while there's still relatively peer-reviewed research available on CBD's health benefits, its fans say it can help treat insomnia, anxiety, pain and seizures. Others say it provides mild relaxation without intoxication. (Marijuana-infused foods are a very different story.)
At Colorado's The Cereal Box, where customers can add a taste-free $3 scoop of CBD powder to their cereal, coffee or milkshake, co-owner Lori Hofer said she spends a lot of time explaining the difference between CBD and THC, the marijuana compound that gets you high.
She said Colorado customers tend to know more about CBD because the state's been at the forefront of marijuana legalization for so many years.
A sign on a display at a Denver-area pet store lists claimed health benefits of CBD, a component of hemp and marijuana plants. TREVOR HUGHES, USA TODAY